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KPV
Lyophilized Powder · lot number on every vial label · COA linked below
Peptides

KPV

CBL-KPV Research Use Only 99.88% purity

Available in 10 mg vials. KPV is a tripeptide (Lys-Pro-Val) fragment of alpha-melanocyte-stimulating hormone. It is used as a reference peptide in laboratory research examining anti-inflammatory signaling in cellular models.

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Compound Information

Technical Specifications
Molecular profile
FormLyophilized Powder
Purity99.88% (UPLC/MS)
Lot KPV10-072026-1 · Jul 10, 2026
Available10mg
OriginSynthesized in the USA
Storage & stability
Protect from light Temperature-sensitive
Lyophilized (powder)
−20°C · stable long-term
Reconstituted
2–8°C · use within 28 days

Sources & References

Peer-Reviewed Research
Biomedical chromatography : BMC
Stability-indicating HPLC assay for lysine-proline-valine (KPV) in aqueous solutions and skin homogenates
2015 · PMID 25298219
Pawar KR, et al.
View on PubMed
PloS one
Structural modification of the tripeptide KPV by reductive "glycoalkylation" of the lysine residue
2018 · PMID 29953505
Songok AC, et al.
View on PubMed
International journal of physiology, pathophysiology and pharmacology
Inhibition of cellular and systemic inflammation cues in human bronchial epithelial cells by melanocortin-related peptides: mechanism of KPV action and a role for MC3R agonists
2012 · PMID 22837805
Land SC
View on PubMed
The Journal of pharmacology and experimental therapeutics
Dissection of the anti-inflammatory effect of the core and C-terminal (KPV) alpha-melanocyte-stimulating hormone peptides
2003 · PMID 12750433
Getting SJ, et al.
View on PubMed
Gastroenterology
PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation
2008 · PMID 18061177
Dalmasso G, et al.
View on PubMed
Inflammatory bowel diseases
Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease
2008 · PMID 18092346
Kannengiesser K, et al.
View on PubMed
The Journal of investigative dermatology
alpha-Melanocyte-stimulating hormone, MSH 11-13 KPV and adrenocorticotropic hormone signalling in human keratinocyte cells
2004 · PMID 15102092
Elliott RJ, et al.
View on PubMed
References are provided for qualified researchers as a starting point for literature review. Canon Bio Labs makes no therapeutic claims and no claims about the contents of cited works. All products are for laboratory research use only.

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For research use only
All products are sold exclusively for laboratory research use by qualified professionals. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. These products have not been evaluated or approved by the FDA.
Canon Bio Labs LLC d/b/a Canon Bio Labs supplies analytical-grade biochemical reference standards and laboratory research materials, sold exclusively for laboratory research and analytical use by qualified research customers. Products are not for human or animal consumption, therapeutic use, clinical use, diagnostic use, dietary supplementation, dosing, injection, ingestion, or administration.
Disclaimer: All products listed on this site are for research purposes only and are not intended for human or animal consumption, dosing, or injection. These products have not been evaluated or approved by the FDA. They are not intended to diagnose, treat, cure, or prevent any disease and are sold solely for in-vitro laboratory research by qualified professionals in accordance with applicable regulations. By purchasing, you confirm you are at least 21 years of age and have a legitimate research purpose. Canon Bio Labs is not a compounding pharmacy or chemical compounding facility as defined under Section 503A of the Federal Food, Drug, and Cosmetic Act, nor an outsourcing facility as defined under Section 503B.
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